Renal bioprinting perspectives and challenges in the treatment of Renal failure

Abstract

3D bioprinting is revolutionizing regenerative medicine, especially in the field of kidney transplants. This technique makes it possible to create functional kidney tissue from the patient's own cells, reducing the risk of rejection and donor dependency. By combining living cells, growth factors, and biomaterials, structures can be generated that mimic the function of a real kidney. Recent research, such as that conducted at Harvard University, has made significant progress in printing functional kidney tissue. However, there are still challenges to overcome, such as optimizing vascularization and regulating this technology.aimThe main objective of this research is to evaluate the potential of renal bioprinting to treat renal failure, both acute and chronic.so that its clinical viability, progress and challenges within the hospital and clinical setting can be evaluated,Through a systematic review of the literature, we seek to identify the advances, limitations and future perspectives of this promising technique. The results obtained suggest that renal bioprinting could become a viable alternative for patients with kidney disease, offering a personalized solution and reducing the need for transplants. In conclusion, renal bioprinting represents a hope for millions of patients with kidney failure. However, further research and collaboration between different disciplines is required to bring this technology to clinical practice and improve the quality of life of patients