Intermittent fasting in the treatment of type 2 diabetes mellitus.

Abstract

The condition of diabetes mellitus (DM) has been characterized as a non-communicable disease (NCD), which is currently the most prevalent morbidity and mortality factor in a common group. Such is the case of diabetes mellitus type 2 (DM2), a silent disease, largely associated with overweight or obesity, forged by a sedentary lifestyle, with hypercaloric eating habits.

Objective: The present research maintains the purpose of determining the effectiveness of IA with the development of a diet scheme of 21 days for the control of the basal glycemia index (IBG) in DM2.

Methodology: It is an experimental correlative research of descriptive type. Where the blood glucose level is evaluated by means of glycated hemoglobin, under informed consent, of those who exercise the treatment of IA. The statistical distinction was made with the nonparametric tests of K-S and Shapiro-Wilk whose purpose was to define the distribution of the variables. The hypotheses were tested by testing the ranges with Wilcoxon signs that measured the means of the indicators of the dependent variable.

Results: Of the 70 patients included in the study, the female group predominated 6 to 1 over the male group suffering from DM2, with an average variability of the superior body mass index (BMI) in women, denoting values of 38.4 and 35.71 respectively. Significant changes in blood glucose indicators could be verified. Glycosylated hemoglobin, weight and waist/hip index; samples were analyzed by blood biochemistry of patients and anthropometric evaluations.

Conclusions: The treatment with IA determines beneficial effects, such as the effect of autophagy, which demonstrated a regularization in blood sugar. However, there is a need for strict monitoring of their application for the side effects of starvation.