Effects of the use of the toxin botulinum type a in the hyperhydrosis: a review bibliography

Abstract

As an introduction we can indicate that hyperhidrosis is a condition that causes excessive sweating unrelated to physical activity or body temperature, affecting the quality of life, generating physical discomfort and social isolation for those who suffer from it. It is classified as primary focal, located in: armpits, hands, feet and face, with no apparent cause although attributed to hyperactivity of the sweat glands, and secondary, caused by underlying diseases. Therapeutic management depends on its severity and includes antiperspirants, medications, non-invasive techniques such as iontophoresis, especially botulinum toxin type A (TB-A), effective for severe cases or those resistant to other treatments and which is the subject of this review, and surgery. last option for extreme cases. As for TB-A, it is a neurotoxin that blocks the release of acetylcholine, a neurotransmitter that stimulates sweat glands, so it is applied through injections in the affected area. Visible effects occur between 2 and 4 days, with an average duration of the effect of 4 to 8 months. Adverse reactions are generally mild, it is contraindicated in pregnancy, lactation, allergy to TB-A and neuromuscular diseases. The main objective is to analyze the most recent aspects in the use of botulinum toxin type A (TB-A) in the treatment of hyperhidrosis. Materials: systematic bibliographic review of documents from societies, journals and scientific studies in the field of dermatology, related to non-surgical therapy of hyperhidrosis and oriented to the use of botulinum toxin type A (TB-A). Regarding the results, we can indicate that the application of TB-A is considered a safe treatment for hyperhidrosis. Conclusion: the use of botulinum toxin type A is a good treatment for hyperhidrosis, however its treatment is temporary