The best scientific evidence, in the face of SARS-Cov-2 pendemic

Abstract

Introduction The new coronavirus epidemic (SARS-CoV-2), first reported in December 2019 in Wuhan,
China, and which has been declared a public health emergency of international concern by the World Health
Organization, shows a substantial morbidity and mortality, for this reason it is essential to deepen the
epidemiological, clinical aspects of diagnosis and treatment to face and overcome this scourge.

Objective: Review the best published medical evidence and analyze the behavior of the SARS-Cov-2
pandemic, its epidemiology, isolation, clinical manifestations, complications, the most significant elements
for its diagnosis and the new options to learn and apply these experiences in new epidemics.

Material and methods: A systematic search was performed on the PubMed, ProQuest, Embase, Redalyc,
Ovid, Medline, DynaMed and ClinicalKey, EMBASE, LILACS databases during the period 2019-2020 in the
international, regional and local context.

Results: The systematic review of articles provided a total of 100 records, of which 62 were eligible; of these,
12 were not relevant to the subject matter of this review, so 50 were included.

Conclusions: The disease caused by SARS-Cov-2, despite its high mortality, can be prevented with isolation,
diagnosed in a timely manner and effectively treated, which will reduce its epidemiological impact
worldwide. There is a potential therapeutic arsenal in the experimentation phase with promising results.